Glomerular Disease, Symptoms and Causes
Glomerular disease refers to various diseases including glomerulosclerosis and chronic and acute glomerulonephritis. Kidneys are made up of millions of nephrons that filter and remove fluid and waste from the kidneys and turn it into urine. When glomeruli are damaged, red blood cells can leak into the urine and waste products can begin to build up in the blood. There are two major types of glomerular diseases, both can lead to kidney failure:
Glomerulonephritis is the inflammation of the membrane tissues of the glomeruli. Symptoms of acute glomerulonephritis come on suddenly and may be temporary or reversible. Symptoms of chronic glomerulonephritis come about slowly over time.
Glomerular Disease Symptoms
The symptoms of glomerular disease include:
- Foamy urine: This indicates large amounts of protein in the urine, a condition called proteinuria
- Pink or cola-colored urine: This indicates the presence of blood in the urine, a condition called hematuria
- Swelling in the hands, ankles: This swelling, known as edema, often occurs at the end of the day. Swelling around the eyes can be noticeable up awakening
- Reduced glomerular filtration rate: This indicates inefficient filtering of wastes from the blood
- Hypoproteinemia: Low blood protein
Glomerular Disease Causes
Many different kinds of diseases can cause swelling or scarring of the nephron or glomerulus.
Glomerular diseases include many conditions that are the result of various genetic and environmental causes. Glomerular disease can be caused by an infection or a drug that is toxic to the kidneys. It can be caused by diabetes, lupus and other systemic diseases that affect the entire body. Sometimes glomerular disease is idiopathic, which means it occurs without an apparent associated disease.