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Hematopathology

The Division of Hematopathology in the Department of Pathology at North Shore-LIJ Health System is experienced in all aspects of the diagnostic evaluation of patients with hematologic disorders of the blood, bone marrow, lymph nodes and other tissues. This division uses immunohistochemical, flow cytometric and cytogenetic/molecular techniques to evaluate hematologic disorders. We also deliver the highest quality of clinical hematology laboratory services.

The Division of Hematopathology is committed to strong person-to-person working relationships with hematologists and oncologists. Our testing and consultation services assist treating physicians as well as hematopathologists confronted with difficult diagnostic problems in leukemia and lymphoma.

We are active in the teaching of hematopathology to pathology residents, hematology/oncology fellows (adult and pediatric), medical students and laboratory technologists. Our goals include expanding scholarly study of hematologic disorders and collaboration with those involved in research in this exciting subspecialty.
 

Experience

Many years of experience working closely with pathologists, as well as with the treating oncologists and hematologists, has enabled our hematopathologists to understand both the diagnostic complexities and the practical implications in this extremely complex area. We can help determine not only the most appropriate test for diagnosis, but also the circumstances in which additional costly testing may not be needed. We are always available to discuss the special features of any case.
 

Expertise

Expert Consultation

  • The Hematopathology Division is directed by Dr. Judith Brody, a recognized hematopathologist with particular expertise in bone marrow pathology and flow cytometric diagnosis of hematologic malignancies.
  • Drs. Filiz Sen, Silvat Sheikh-Fayyaz, Peihong Hsu and Xinmin Zhang are board certified hematopathologists with expertise in all aspects of diagnosis of hematologic disorders.
  • Surgical pathologists Drs. Jela Bandovic, Maria Navarro, and Morris Edelman bring to the division additional expertise in the diagnosis of lymphoid malignancy.

Although we have expertise in the appropriate application of state-of-the-art technology to the diagnosis of leukemia and lymphoma, we also are experts in the morphologic and immunohistochemical diagnosis of these tumors. We believe that excellent morphologic analysis is essential to the interpretation of ancillary techniques and that it continues to provide the cornerstone to diagnosis.

Special Capabilities

The Flow Cytometry Laboratory uses four-color multiparameter analysis to detect malignant hematopoietic cells in a manner most appropriate for classification.

The laboratory performs more than 5,000 tests per year on the flow cytometric analysis of hematologic disorders (performed on blood, bone marrow, lymphoid tissue, fine needle aspiration, body fluids and CSF, GI and skin biopsies). Other flow cytometric tests performed by the laboratory include routine lymphocyte subset analysis and CD34 enumeration.

Our hematopathologists also works closely with the Cytogenetics and Molecular Diagnostics Laboratories under the direction of Jordan Laser, MD, Associate Medical Director, Core Laboratory (Sr. Director, Division of Cytogenetics and Molecular Pathology) and Chandrika Sreekantaiah, PhD (director of cytogenetics).

Timely Results

Test results generally can be supplied in one or two days from receipt of sample, depending on the nature of the workup performed. If requested, preliminary assessment can be given the same day. Flow cytometric results are available within hours, if needed. Phone reports are routine, and hard copy is usually available by fax the following day.

Reporting

We provide a multidisciplinary approach to the diagnosis of leukemia and lymphoma, aided by our close collaboration with the Cytogenetics, Immunopathology, and Molecular Diagnostics Laboratories. Equally crucial, our faculty is expert in analyzing and interpreting the results provided by this state-of-the-art technology.

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